Insights

When a Single Diagnosis Doesn’t Tell the Whole Story: Utility of Syn-One Test™ in Patients With Dual Neurologic Diseases

By December 7, 2021 No Comments

When a Single Diagnosis Doesn’t Tell the Whole Story: Utility of Syn-One Test™ in Patients With Dual Neurologic Diseases

In CND Life Sciences’ newest case study, Dr. Todd Levine describes the case of a 64-year-old woman with a long history of multiple sclerosis. She had tried several treatments over the previous three decades with varying degrees of success and exhibited a classic relapsing-remitting disease course.

However, she began to notice new symptoms, including weakness in her legs and a tremor in her both her arms. Her husband noted that she was becoming more forgetful and would get disoriented in unfamiliar surroundings. The most likely explanation was that she was advancing to secondary-progressive MS, but despite being treated accordingly, her symptoms did not improve. Was she failing to respond to treatment, or was it possible that another neurological disorder was causing her newly progressive symptoms?

Diagnosing neurodegenerative disorders is challenging. An array of clinical presentations may suggest different disorders, and overlapping symptoms make it difficult to pinpoint a cause. In this case, however, the patient already had a correct diagnosis. Her new symptoms may very likely have been caused by her MS, but because they also suggested parkinsonism, her neurologist ordered a Syn-One Test. The Syn-One Test is a simple, minimally invasive diagnostic tool designed to detect the family of disorders known as synucleinopathies, which includes Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy, pure autonomic failure, and REM sleep behavior disorder.

Find out how the results helped clarify the treatment approach and significantly impacted the patient’s ability to perform activities of daily living.

See the case study