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Synuclein-One Study

Synucleinopathies are a group of neurodegenerative disorders that result from the deposition of phosphorylated alpha-synuclein within the central and peripheral nervous systems. Synucleinopathies affect over 2 million people in the US and include Parkinson’s disease, multiple system atrophy, dementia with Lewy bodies, pure autonomic failure. Diagnosis is often made late in the disease, making diagnostic testing an urgent unmet need.

Nurse talking to a patient

About the Study

The Synuclein-One Study is a large scale, prospective, cross-sectional, multicenter validation study of the Syn-One Test® in 428 subjects with synucleinopathies and 120 control subjects at over 30 site locations throughout the US. The results of the study will be used to advance the clinical utility and application of the Syn-One Test for neurology practices and patients nationwide.

Participants with a diagnosis of Parkinson’s disease, multiple system atrophy, dementia with Lewy bodies, or pure autonomic failure
Participants who are considered healthy individuals to
act as a control group

We would like to thank the following sites for their participation.

Aventura Neurologic Associates
Aventura, FL

Boston Medical Center Dept. of Neurology, Parkinson’s Disease and Movement Disorder Center
Boston, MA

Cenexel RMCR
Englewood, CO

CND Life Sciences
Scottsdale, AZ

Duke University School of Medicine
Durham, NC

Evergreen Health
Kirkland, WA

Lahey Hospital & Medical Center
Boston, MA

Mayo Clinic Rochester
Scottsdale, AZ

MD First Research
Chandler, AZ

Movement Disorders Center of Arizona
Scottsdale, AZ

New York University School of Medicine
New York, NY

Dept. of Neurology, NorthShore University Health System 
Chicago, IL

Pacific Neuroscience Institute, Providence St. John’s Health Center
New York, NY

Parkinson’s Disease & Movement Disorders Center of Boca Raton
Boca Raton, FL

Parkinson’s Disease Treatment Center of SWFL
Port Charlotte, FL

Providence Neurological Specialties West
Portland, OR

South Shore Neurologic NYU Langone
Patchogue, NY

Stanford University Dept. of Neurology and Neurological Sciences
Palo Alto, CA

Swedish Neuroscience Research
Seattle, WA

Texas Movement Disorders Specialists
Georgetown, TX

The Neurology Center of Southern California
La Jolla, CA

UCSD Dept. of Neurosciences and Shiley Marcos ADRC
San Diego, CA

University of California San Francisco
San Francisco, CA

UF Health Norman Fixel Institute for Neurological Diseases, Dept. of Neurology, UF College of Medicine
Tampa, FL

University of Iowa Hospital and Clinics
Iowa City, IA

University of Utah Dept. of Neurology
Salt Lake City, UT

UT Southwest Medical Center
Dallas, TX

Vanderbilt University Medical Center
Nashville, TN

© CND Life Sciences | Diagnostic Insights for Life | All rights reserved.

© CND Life Sciences | Diagnostic Insights for Life | All rights reserved./