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Syn-One Test® Featured in The Scientist Magazine Innovation Spotlight

By August 27, 2025No Comments

Syn-One Test® Featured in The Scientist Magazine Innovation Spotlight

An article about the Syn-One Test was published this month in the Innovation Spotlight section of The Scientist, a magazine written for life science professionals that covers “…the latest scientific discoveries, trends in research, innovative techniques, new technology, business, and careers.”

In the article, Christopher Gibbons, MD, MMSc, Chief Scientific Officer and Co-Founder of CND Life Sciences, describes the challenges of diagnosing neurodegenerative disorders, including overlapping symptoms and a lack of accurate diagnostic tools. Further, neurological conditions are typically more difficult to diagnose in the early stages, which hinders appropriate treatment selection and makes it difficult for patients to plan for their future. “…PD often unfolds over 20 years, while MSA progresses rapidly, with a median survival of just 3-7 years. For patients and families, knowing the specific diagnosis has a tremendous impact on life planning,” writes Dr. Gibbons.

Tests that detect biomarkers, such as the Syn-One Test® for phosphorylated alpha-synuclein (P-SYN), have emerged as a promising way to more accurately diagnose certain neurological disorders, even very early in the course of the disease.

Dr. Gibbons goes on to describe how biomarker tests can be used in the drug development process. Accurate diagnoses ensure that pharmaceutical trials evaluate the right patients at the right time, reducing the possibility that a medication fails to show an effect because it wasn’t studied in the intended population. And if a treatment is designed to target a specific biomarker such as P-SYN, the Syn-One Test may be useful in measuring the drug’s effect. “The more we can understand these diseases at a biomarker level, the better we can predict disease progression and develop precision medicine,” says Dr. Gibbons.

The article also covers the advantages of skin biopsy vs other testing modalities such as brain imaging or testing cerebrospinal fluid, the latest findings from research using the Syn-One Test, and the exciting developments on the horizon for CND.

Read the article