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Real-World Impact of the Syn-One Test®: Four Patient Cases

By January 6, 2023October 5th, 2023No Comments

Real-World Impact of the Syn-One Test®: Four Patient Cases

Clinicians often encounter patients who do not fit neatly into one diagnostic bucket. These cases may present with symptoms of more than one disease, or they may have symptoms that only partially fulfill diagnostic criteria. These diagnostic dilemmas make it difficult to provide answers to patients and determine the best course of action, and patients may live with life-altering symptoms for years without an explanation or an appropriate treatment plan. Below we introduce four real-world cases where neurologists used the Syn-One Test to improve their diagnostic clarity.

A 64-year-old woman with a 30-year history of relapsing-remitting multiple sclerosis (MS) presents with worsening gait instability and tremor. MRI scans show no new lesions within the last few years. Although secondary progressive MS is the most likely diagnosis, the nature of the rest tremor suggests a second disease process might be present. See case study

A 65-year-old male with type 2 diabetes presents with both resting and intention tremors. His DaTscan results are borderline abnormal, leaving the diagnosis undetermined. His doctor needs a more objective test to help determine if Parkinson’s disease is the cause. See case study

A 67-year-old female with hypertension and well-controlled type 2 diabetes for the past three years presents with three syncopal episodes in the past six months. The events all occurred when standing up. Her EKG, EEG, loop monitor, and stress test are all normal. Is this a diabetic autonomic neuropathy or could there be a distinct cause for her neurogenic orthostatic hypotension? See case study

A 72-year-old female is brought in by her family with concerns about behavioral changes that have been progressive over the past six months. She has short-term memory impairment, difficulty sleeping, and insists she sees insects in the house. Her doctor suspects that the cause could be Alzheimer’s disease or dementia with Lewy bodies and needs to differentiate between the two in order to develop an appropriate treatment plan. See case study

Find out how the Syn-One Test helped lead to a more objective and accurate diagnosis in each case, clarifying the treatment plan and making a tangible difference in patients’ lives.

See the case studies